
Hyperadrenergic POTS: What the Evidence Actually Says, and What Actually Helps
Your heart races when you stand up, but it’s everything else that’s harder to explain. The visible shake in your hands. Surges that feel like

Your heart races when you stand up, but it’s everything else that’s harder to explain. The visible shake in your hands. Surges that feel like

Three in the morning, and you’re lying there with one hand pressed against the back of your skull, trying to work out if your head

It’s not uncommon for those with hypermobility to have difficulty with swallowing, voice, reflux, and last but not least, that maddening feeling of a lump

If you have hypermobility and your head is a regular problem, you’ve probably had it explained to you in one of two ways. Either it’s

Why people with POTS sleep so badly, what the autonomic nervous system does overnight, and what the evidence actually supports for fixing it. The honest version.

A 2026 state-of-the-art review from an international team of 11 researchers has updated the diagnostic framework for POTS. Here is what actually changed, what it means for people struggling to get diagnosed, and what the review still does not address.

One in four people with hEDS carries diagnoses of all three: hypermobile EDS, POTS, and MCAS. The overlap is well documented. The mechanisms are still being worked out. Here is what the research actually says.

It’s not uncommon for those with hypermobility and EDS to have difficulty with their joints, their gut, getting enough energy, and last but not least,
It’s not uncommon for those with fibromyalgia and hypermobility to feel oddly disconnected from their own bodies, struggling to put a name to what they’re